Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0f290b488d9fdf85510699f01f99bff3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b66a95c8a6f795285529075b6118cf6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac198f217e89b7813a61b4b6b80312cf http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c73019ad9c121b6723e3cf570d2a1f7e http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_15cd5649aae84dd3bd26f85e5a89fe34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e035457406455ea05989c01cb90c8f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ca6158b5661578efae3154e3d030c98 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-573 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-50 |
filingDate |
2000-03-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e61bb378d85f91f026c7f8029678c9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d62628ae037abc697f3e51345816204d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8985c3ba29dd30317e397f282d54f9ef http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a53dc5e152f95d6313d4a35cd5908bf5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0bf22630d318df7868af678280e424b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fcb04172c0dcb4b1f749d1388b225bc |
publicationDate |
2000-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0056864-A2 |
titleOfInvention |
Methods for altering substrate specificity of phosphoinositide-dependent-protein kinase 1 (pdk1) |
abstract |
A method of altering the substrate specificity of phosphoinositide-dependent protein kinase 1 (PDK1) wherein the said PDK1 is exposed to a polypeptide which comprises the amino acid sequence Phe/Tyr-Xaa-Xaa-Phe/Tyr-Zaa-Phe/Tyr wherein Zaa represents a negatively charged amino acid residue. The PDK1 with altered substrate specificity is capable of phosphorylating the underlined residue in a polypeptide with an amino acid sequence corresponding to the consensus sequence Phe/Tyr-Xaa-Xaa-Phe/Tyr-Ser/Thr-Phe/Tyr. The PDK1 with altered specificity may be useful in screening assays and for phosphorylating substrates having the above consensus sequence. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7794995-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7792665-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0144497-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20030084133-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03104481-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03106669-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03104481-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0144497-A3 |
priorityDate |
1999-03-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |