abstract |
A cell activity assay apparatus ('CAAA') and method using electromagnetic radiation detection beams to measure the cell activity, e.g., chemotactic response, includes an opaque membrane having a plurality of off-axis pores which prevent experimentally significant amounts of the electromagnetics radiation from traversing the membrane. The membrane is fabricated from opaque films that have been either ablated with substantially off axis excimer laser electromagnetic radiation to form pores, or bombarded by substantially off-axis charged particles and then etched to form pores. |