| abstract |
This invention relates to newly identified prostate or prostate cancer related polynucleotides and the polypeptides encoded by these polynucleotides herein collectively known as 'prostate cancer antigens', and to the complete gene sequences associated therewith and to the expression products thereof, as well as the use of such prostate cancer antigens for detection, prevention and treatment of disorders of the prostate, particularly the presence of prostate cancer. This invention relates to the prostate cancer antigens as well as vectors, host cells, antibodies directed to prostate cancer antigens and recombinant and synthetic methods for producing the same. Also provided are diagnostic methods for diagnosing and treating, preventing and/or prognosing disorders related to the prostate, including prostate cancer, and therapeutic methods for treating such disorders. The invention further relates to screening methods for identifying agonists and antagonists of prostate cancer antigens of the invention. The present invention further relates to methods and/or compositions for inhibiting the production and/or function of the polypeptides of the present invention. |