| abstract |
Novel nitrile derivatives useful as intermediates for the preparation of medicinal compounds including N,N-substituted cyclic amine derivatives and phenylacetonitrile derivatives, or the like. Specifically, nitrilocarboxylic acid derivatives, nitrilo ester derivatives and nitrilo alcohol derivatives, as represented by general formula (I), (wherein R?1 and R2¿ are each a substituent; m is an integer of 0 to 6; n is an integer of 0 to 5; and R3 is carboxyl, lower alkoxycarbonyl or hydroxymethyl). |