| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e9b2eb31e242fafacbafa0aeab54d11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71269ccff403541c5a3d6dfaaa13ce38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b8be6a6c990669567cc455d32b00535e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fc8b4f0ae7843f86b382231535cba9da |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M41-48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M29-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5014
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5044 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-06 |
| filingDate |
2000-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d2518770efb98c58ce502eb010de2e9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2bd0d11f8e2cfdbe7fec18367c2ec8fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b238695940674555a5da5ab97cd4177b |
| publicationDate |
2000-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0053797-A1 |
| titleOfInvention |
Method for the in vitro testing of active ingredients, corresponding device and their use |
| abstract |
The invention relates to a method for the in vitro testing of active ingredients in cells, which includes at least the following steps: provision of a cell culture dish having an inner chamber and an outer wall as well as a first and a second membrane system positioned in the inner chamber, a cell culture chamber being configured between the membrane systems and the inner wall of the inner chamber; introduction of a cell culture and a cell culture medium into the cell culture chamber; addition of a liquid nutrient medium to the cell culture chamber; removal of products of metabolism by means of the first membrane system; delivery of at least one gaseous medium to the cell culture chamber by means of the second membrane system; addition of at least one active ingredient into the cell culture chamber in accordance with a set active- ingredient concentration-time curve; and monitoring of cell vitality. The invention also relates to a device and to the use of said device for testing the effect of idarubicin on the leukaemic cell line CCRF CEM. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10631974-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11124752-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8163536-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2016503299-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2014193415-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8048673-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8911994-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10626358-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10729536-B2 |
| priorityDate |
1999-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |