| abstract |
This invention discloses a compound having general formula depicted in Formula (I), wherein G is a spacer moiety selected from the group consisting of C1-C7 alkyl, C2-C7 alkenyl, C2-C7 alkynyl, C1-C7 alkyl-NHCO-, and -SO2-, T is a six-membered ring or a seven-membered ring containing two ring nitrogens and belonging to formula (a), with said T ring being c onnected to said G moiety at either a ring carbon atom of ring T or a ring nitrogen atom of ring T: wherein n is 1 or 2. These compounds have excellent histamine-H3 receptor antagonist activity. |