Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fa2ea32e3cda1d0118f53c48b589cfed http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a4b25ffde107e40983abe9c7eaa73581 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_577821cf81fda3e1088e6ed08bcd136b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4ab2d714181eae13dd7cdead6e6fdaf3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ea5ca0c61cdfe3efda0914ab44a1df34 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09J151-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08F251-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F251-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09J151-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
filingDate |
2000-02-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_691c412da240ad69af1305d9d178de67 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da9ea4e10cea69890781a357b74bdbd7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dce6c76422132653d77a4b0ac52bd140 |
publicationDate |
2000-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0047644-A1 |
titleOfInvention |
A biocompatible adhesive system and a bioadhesive drug delivery system with controllable release |
abstract |
Bioadhesives and controlled release drug delivery systems were prepared from a series of starches grafted with acrylic monomers by two initiation methods: chemical and radiation. In general, the grafted starches prepared by chemical initiation with a Ce4+/Ce3+ redox system showed a lower bioadhesion and released the model drugs in relatively shorter. These materials can be characterized by measuring their swelling in water and at various pH values and the molecular weight of the branched acrylic polymer grafted onto the starch can also be determined. Bioadhesives and controlled release drug delivery systems were also prepared from a series of starches from various sources grafted with acrylic acid by radiation with 60Co. These materials had better bioadhesive and controlled drug release properties. The effect of mono- and divalent cations present in the graft copolymers indicated a particularly high potential as bioadhesive materials for oral drug delivery systems. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0158430-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6284235-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02098272-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111569797-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111569797-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102863933-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102863933-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7207941-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6824792-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104804137-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7576067-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7846478-B2 |
priorityDate |
1999-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |