Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c8cbbf2290b3f3a9988da29598baa2c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-16122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10322 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate |
2000-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7b42cf56667d180b3752e207b1c76b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08983fba4444b28c6070a7f8a468c704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6337545fe1c0e694639a977fe51a796a |
publicationDate |
2001-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0046384-A9 |
titleOfInvention |
Nucleic acid uptake and release vehicle |
abstract |
A nucleic acid uptake and release vehicle comprising a ligand for a receptor covalently bonded by an amide linkage to an influenza virus hemagglutinin endosomolytic peptide is disclosed, which optionnaly may also comprise a polylysylleucyl peptide so as to provide additional sites for nucleic acid attachment; as well as a nuclear localization signal peptide so as to enhance intranuclear localization of delivered nucleic acid. The vehicle can be utilized to enhance the intracellular delivery of nucleic acid molecules. |
priorityDate |
1999-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |