http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0044240-A1
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_259c37dd7dd9fe228f186e828c84bbb7 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
filingDate | 2000-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dadea2483ec1fb6aa563eecf6029d042 |
publicationDate | 2000-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | WO-0044240-A1 |
titleOfInvention | Treatement of colic and gut spasm in horses and other vertebrates |
abstract | The present invention presents pharmaceutical compositions and methods of use of those compositions to treat colic in horses and other vertebrates, including humans. In a preferred embodiment, a first composition, made with an anti-spasmodic (such as dicyclomine), an analgesic, an anti-inflammatory, and an anxiolytic (such as alprazolam), is administered via rectal suppository or other route. In addition, an intestinal smooth muscle relaxant, or a nitric oxide donor may be used in the composition. Alternatively, a second composition is made of an analgesic and an anxiolytic, and, optionally, one or more components selected from an anti-spasmodic, an anti-inflammatory, an intestinal smooth muscle relaxant, and a nitric oxide donor. In another preferred embodiment, administration of the first composition is followed by administration of a second composition that is a laxative. Typically, the laxative is administered from about 10 minutes to about 2 hours after administration of the first composition, and preferably is by oral administration. Alternate anti-spasmodics, analgesics, anti-inflammatories, and anxiolytics may be used beneficially as well. For non-spastic colics, the anti-spasmodic may be eliminated. The use of nitric oxide donors are particularly beneficial in necrotizing enterocolitis. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1499331-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1499331-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006130982-A1 |
priorityDate | 1999-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 707.