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filingDate 2000-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2000-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber WO-0042897-A2
titleOfInvention Method and apparatus for measurement of microtome performance
abstract A method and apparatus for monitoring (30) and evaluating (36a, 42a) the performance and condition of histology laboratory microtomes and microtome accessories including knives (32d), motor drives, and illumination devices (32b). Irregularities in an image of the surface of a block (40a) mounted on the microtome are detected and characterized (40b), the block having been subjected to mechanical sectioning by the microtome to produce a cut block face. The image of light reflected from the surface of the block, either specular or non-specular, is recorded (raw specular image) and subjected to graphical analysis to extract, quantify, and interpret patterned features, including those indicating anomalies in the function of the microtome, its accessories, or the tissue block itself (42b, 42c, and 42d)..
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