Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f831af34ee2c26f385f7fe130aef8d9a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_879744f55782c7abd4187ef5eb993e63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_391838f77000d10152436003c676763d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d6645ce16dbbcebca4cd8d594d264e9d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9a013b256df0ee5119d0e38f781bddcb http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8baf67d4f2c6fbaa00b3ceec77fd98ad |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1089 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6875 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B20-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B20-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F17-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6811 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
filingDate |
2000-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf823eb77d187e4c403e0dc5e773b3a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c8ab0841275222e854355aa1bc1943e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_564ca33f117d26a347a3f04b8962c831 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26b4e730cbecd76c284d519ca36242a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c36cef07ce47a0ad92df70331eb4336 |
publicationDate |
2002-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0042219-A9 |
titleOfInvention |
Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
abstract |
The invention provides criteria and methods for selecting optimum subsequence(s) from a target for targeting by a zinc finger protein. Some of the methods of targetgene site selection seek to identify one or more target segments having a DNA motif containing one or more so-called D-able subsites having the sequence 5'NNGK3'. Other methods of the invention are directed to selection of target segments within target genes using a correspondence regime between different triplets of three bases and the three possible positions of a triplet within a nine-base site. In another aspect, the invention provides methods of designing zinc finger proteins that bind to a preselected target site. These methods can be used following the preselection of target sites according to the procedures and criteria described above. The methods of design use a database containing information about previously characterized zinc finger proteins. |
priorityDate |
1999-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |