| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3873abaff397acbfffa1595a12cfef41 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1007 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 |
| filingDate |
2000-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15133cd91bd7332d17f656d556ae89d9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f479e5608c1e49b59fb0d26b3ecf390
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20e27fd0aa978367efba0f16233fe9b7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff28a79f8627e96d751f44895bab8f11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f79831cce1e750200dec7166a09f797 |
| publicationDate |
2000-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0042196-A2 |
| titleOfInvention |
Human methionine synthase reductase: cloning, and methods for evaluating risk of neural tube defects, cardiovascular disease, cancer, and down's syndrome |
| abstract |
The invention features a novel gene encoding methionine synthase reductase. The invention also features a method for detecting an increased likelihood of hyperhomocysteinemia and, in turn, an increased or decreased likelihood of neural tube defects, cardiovascular disease, Down's Syndrome or cancer. The invention also features therapeutic methods for treating and/or reducing the risk of cardiovascular disease, Down's Syndrome, cancer, or neural tube defects. Also provided are the sequences of the human methionine synthase reductase gene and protein and compounds and kits for performing the methods of the invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107383199-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107699612-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108251541-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013086582-A1 |
| priorityDate |
1999-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |