| abstract |
The present invention provides an anti-thrombogenic coating composition for blood-contacting surfaces. The coating comprises a covalent complex of from 1 to 30 hydrophobic silyl moieties of formula (I), wherein R1 is an C1-8 alkyl or C6-32 aryl group, each R2 is independently selected from the group consisting of C1-8 alkyl and C6-32 aryl, R3 is N or O, and n is a number from 1 to 10, directly bound to a heparin molecule via covalent bonding. |