| abstract |
The present invention discloses a synthetic molecule consisting of a charged unit covalently linked to a moiety and methods of producing the same. Specifically, a glycosaminoglycan chain(s) is covalently linked to a moiety to synthesize proteoglycan. Examples of the moiety are human serum albumin, β2-microglobulin, avidin, a peptide and a lipid. Also provided are various therapeutical applications of the synthetic molecules. |