Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2e3bef8bb4291a88571adf3ffad84681 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f6fbe16bb6eb71437624a2b0a68a2ae5 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-16 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-191 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-295 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
filingDate |
1999-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92f3a177956df980c3423cf32ec851ed |
publicationDate |
2000-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0038657-A1 |
titleOfInvention |
Method for preparing an effervescent granulate comprising iron gluconate, granulate thus obtained and tablets containing the same |
abstract |
A method for preparing an effervescent granulate comprising ferrous gluconate as pharmacologically active ingredient, and citric acid and sodium bicarbonate as effervescent system, by means of wet granulation in a fluid-bed granulator, wherein the said method comprises the steps of I) feeding a mixture comprising ferrous gluconate, citric acid and sodium bicarbonate into the said granulator which is simultaneously fed with a flow of air heated to about 70 °C and having a moisture content of ∫1.0 g/kg; II) wetting the said mixture with nebulized water when this mixture has reached a temperature of about 35 °C; III) evaporating off the nebulizing water, while keeping the temperature of the said mixture substantially constant at 35 °C; IV) repeating steps II and III until a granulate with the desired features is obtained; and V) drying the said granulate with air heated to about 80 °C until its moisture content is ≤0.5 % by weight. Granulate thus obtained and tablets containing the same. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6828130-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6416981-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10392416-B4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03080073-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7267970-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GR-20000100238-A |
priorityDate |
1998-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |