| abstract |
Compounds represented by general formula (I), and salts and esters thereof; processes for the preparation of the three; and analgesics, antagonists against the tolerance to narcotic analgesics including morphine, antagonists against the dependence on narcotic analgesics including morphine, potentiators for analgesic action, antiobestics, cerebral function ameliorators, Alzheimer's disease remedies, nootropics, schizophrenia remedies, Parkinson's disease remedies, chorea remedies, antidepressants, diabetes insipidus remedies, polyuria remedies, and hypotension remedies, which contain the compounds, salts or esters as the active ingredient. In said formula Cy is an optionally substituted carbalicyclic group; (a) is an optionally substituted nitrogenous heteroalicyclic group; R1 is hydrogen, optionally substituted lower alkyl, or the like; R2 is hydrogen or lower alkyl; and X is hydrogen, halogeno, or the like. |