| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ca2e4410855da087e11bf3eea8933fa
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_63d9939e74035bbe6ba0014c1bcc694d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4896365db269695a5e0275aa46cdd24c |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-707 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-70 |
| filingDate |
1999-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07822c381c23f0dadb6aacfab21cb05b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df04e0aa9fef0bc2b1a54d6b8adfe426 |
| publicationDate |
2000-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0033635-A2 |
| titleOfInvention |
Primer-independent rna synthesis catalyzed by hcv polymerase |
| abstract |
Provided are methods for identifying inhibitors of primer-independent hepatitis C virus RNA-dependent RNA polymerase de novo RNA synthesis activity, methods for inhibiting the polymerase using such inhibitors, and methods for inhibiting hepatitis C virus replication. These methods employ homopolyC templates; homopolyU templates; synthetic heteropolymeric RNA templates comprising a cluster of cytidylate nucleotides, a cluster of uridylate nucleotides, or a mixed cluster of cytidylate and uridylate nucleotides; and synthetic or naturally occurring RNA templates comprising an RNA synthesis initiation pyrimidine nucleotide. Reactions can be carried out in buffers containing Mn++ alone, or in combination with Mg++ ions. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7985541-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0183736-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2005095655-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0183736-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007530049-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0246461-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0246461-A2 |
| priorityDate |
1998-12-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |