Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e94e81870297af08b76d547aa9c337b http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c410ef1091c8401e46e2d1ce6b962c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_07c9542186133097bd6bbb7d92393090 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2227-101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2267-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2730-10122 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-0275 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-8509 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-02 |
filingDate |
1999-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_983b1a3e358f58385d2bac92281da12d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b515eed407d8401280d3b8fe97e05cec |
publicationDate |
2000-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0030437-A1 |
titleOfInvention |
Transgenic animals |
abstract |
The present invention provides improved methods and compositions for the generation of transgenic non-human animals. The present invention permits the introduction of exogenous 5nucleic acid sequences into the genome of unfertilized eggs (e.g., pre-maturation oocytes and pre-fertilization oocytes) by microinjection of infectious retrovirus into the perivitelline space of the egg. The methods of the present invention provide an increased efficiency of production of transgenic animals with a reduced rate of generating animals which are mosaic for the presence of the transgene. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103068985-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108070617-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112342238-A |
priorityDate |
1998-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |