abstract |
The invention relates to a novel method of producing the compounds of formula (I) wherein the substituents have the following meanings: n is 0,1 or 2; R<1>, R<2> represent C1-C6-alkyl; R<3>, R<4>, R<5> are hydrogen, C1-C6-alkyl or R<4> and R<5> together form a bond; R<6> is C1, Br. Said method comprises the following steps: a synthesis sequence starting from 1,2-dialkylbenzenes of formula (II); halogenation to form 3,6-dihalogen-1,2-dialkylbenzenes; haloalkylation to form benzyl bromides; oxidation to form benzaldehydes; reaction with alkenes to form isoxazoles; reaction to form thioethers and optionally oxidation to form sulfenyl or sulfonyl derivatives of formula (I). |