| abstract |
The invention concerns compounds of general formula (I) wherein: A represents a hydrogen atom, an azido, a halogen, a hydroxy, a thiol, an amino, a phenyl, a C1-C6 alkyl, C1-C6 alkylamino, di(C1-C6 alkyl)amino, hydroxylamine, C1-C6 alkyl hydroxylamine, N, O-C1-C6 dialkyl hydroxylamine, C1-C6 alkoxy or C1-C6 alkylsulphanyl group; B and D represent independently of each other a hydrogen atom, a phenyl, a C1-C6 alkyl, C2-C6 alkenyl, C1-C6 fluoroalkyl or C1-C6 perfluoroalkyl group, or together form an oxo; R1 represents a hydrogen atom, a halogen, a carbonyl, a cyano, a carboxamide, a C1-C6 alkyl, C2-C6 alkenyl, C3-C6 cycloalkyl, C1-C6 alkoxycarbonyl, C1-C6 hydroxyalkyl, C1-C6 alkoxy, C1-C6 alkoxy C1-C6 alkyl, C1-C6 fluoroalkyl, C1-C2 perfluoroalkyl or CF3(OH)CH group, or R1 and R2 together form, with the carbons whereto they are bound a phenyl; R5 and R6 represent, independently of each other, a hydrogen atom, a C1-C6 alkyl, C2-C6 alkenyl, C3-C6 cycloalkyl, C3-C6 cyloalkenyl, C1-C6 fluoroalkyl, C1-C2 perfluoroalkyl group or R5 and R6 together form a C2-C6 alkylene, C3-C6 alkenylene chain to produce with the nitrogen whereto they are bound a heterocycle, said heterocycle being optionally substituted by a C1-C4 alkyl group. The invention has therapeutic applications. |