http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0027859-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4a8a1cb36c35065d98f072e3cf942055 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_785ac2b35073f5a6d251678e6fb31b6f |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-11 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-00 |
| filingDate | 1999-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4828ef977c53d9f805ae653ab4261213 |
| publicationDate | 2000-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0027859-A1 |
| titleOfInvention | Improved processes for the synthesis of oligomeric compounds |
| abstract | The present invention provides synthetic processes by which oligomeric compounds, having at least one phosphodiester or phosphorothioate linkage, are prepared. The synthetic processes use a novel mixture of concentrated ammonium hydroxide and a thiol compound during the deblocking step of all or selected internucleoside linkages. Alternatively, the deblocking is carried out in two steps using a mercapto compound in an aquaeous amine followed by concentrated ammonium hydroxide. Also provided are synthetic intermediates useful in such processes. Novel oxidation procedures to give phosphodiester oligomers are also included. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1176151-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7135565-B2 |
| priorityDate | 1998-11-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 293.