abstract |
A catheter apparatus for the intraorgan administration of medicinal agents, such as cells, genes, drugs, other agents and soluble protein factors such as growth factors into a designated site within an organ approached via entry points in the arterial or venous circulatory system, cut-down sites, surgery, introducer ports during minimally invasive surgery, or body orifices including the mouth, esophagus, trachea, urethra, and anus, etc. The device consists of a catheter device with one or more compartments housing one retractable hollow bore needle for the dispersion of medicinal agents into a target tissue, an anchoring means for stabilizing the end of the catheter to a surface, such as the endocardium, of the target organ and a guiding wire for directing the catheter to a specific location. The control means are located at the proximal end of the inventive device and located external to the patient. |