| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bac93b4bf41c93b89d4e09b174e91ed
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_38d2d7c1025409dabc7964b5154bcfb0
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d830185c6a27d4d7448afaea733ccdf4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e7e80a57de2023e5180143bd5aa5703 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
1999-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_159914d8ce1a79624790897a6fd95b9e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab22ec2ac31755637cbc27bb3719bd2e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90046f120a532fee0ee3c20565b459f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0fe46e5b2044668e795888baf4abbef |
| publicationDate |
2000-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0024778-A1 |
| titleOfInvention |
Hla-a2 and hla-dr specific peptide epitopes from the melanoma antigen trp2 |
| abstract |
Novel HLA-Class I and HLA Class II restricted epitopes of the melanoma antigen tyrosinase-related protein 2 are described. A novel HLA-A*0201 restricted epitopes present in the melanoma antigen tyrosinase-related protein 2 (TRP2) is disclosed. The invention relates to a nine-amino acid peptide designated TRP2 (180-188). The peptide is demonstrated to induce cytotoxic T lymphocytes (CTL) which specifically react with, and lyse, melanoma cells in the context of HLA-A2 or HLA-A*0201. The invention further relates to a nine-amino acid peptide derived from TRP2 which induces helper T lymphocytes in the context of HLA-DR. The invention also relates to diagnostic methods and pharmaceutical compositions which employ the tumor antigen therapeutically and prophylactically. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8604167-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2006119527-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2009511424-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2012180359-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8871211-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7939090-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8097256-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10226519-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9095538-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2015366957-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1377304-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1377304-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9023338-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11096996-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8383768-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9068020-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10137182-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102005041616-B4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102005041616-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9382308-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03016342-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03016342-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-102005041616-A8
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9433667-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7803566-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8067535-B2 |
| priorityDate |
1998-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |