| abstract |
The invention concerns genes, polymorphisms and polypeptides related to central nervous systems disease. Included are the G713 gene, the G713 protein and G713 biallelic markers, as well as biallelic markers located on the human chromosome 13q31-q33 locus, and the association established between these biallelic markers and schizophrenia. The invention also provides means to determine the predisposition of individuals to schizophrenia as well as means for the diagnosis of this disease and for the prognosis and detection of an eventual treatment response to therapeutic agents acting against schizophrenia. |