| abstract |
There are provided according to the invention novel compounds of formula (I), wherein R1 represents C¿1-4?alkyl or C3-8cycloalkyl, R?2¿ represents C¿1-4?alkyl or C3-4alkenyl, R?3¿ represents hydrogen, C¿1-3?alkyl or halogen, and R?4¿ represents C¿1-6?alkyl, processes for preparing them, pharmaceutical formulations containing them and their use in therapy particularly as thrombin inhibitors. |