Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a727fc8ed43cc6e479daaf2f04853df |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6823 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6818 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6823 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
1999-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86309695643f7ca015e05e4cf3debd3d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ec43380b81436808b207949bcf5ec6c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab39afd26471b7d58de66633a1333500 |
publicationDate |
2000-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0015848-A1 |
titleOfInvention |
Nucleic acid ligand interaction assays |
abstract |
Method for determining the relative binding affinities of various ligands to various nucleic acid sequences, particularly in double-stranded form, are described. In a direct binding assay, the effect of adding increasing amounts of a ligand on a signal generated by two 'indicator' oligonucleotides is observed. Also described is a competitive binding assay, in which a competitor oligonucleotide is added to an indicator duplex having a ligand bound thereto. The assays allow the rapid and convenient determination of nucleic acid binding specificities and base pair determinants of specificity of particular ligands. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/AU-2002213096-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6815164-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0229117-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0229117-A2 |
priorityDate |
1998-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |