Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dbc908f6fe204bbabc82787390d5d1f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7963cfb986b89c5a84d7d96e28c1fe28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d350625286def8f8f8172a3d67dd0ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e9953df0349d76f1fc0cf5929f4eb816 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 |
filingDate |
1999-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f8bdbdad2d238f2b623a1bf756e7b6a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9b2454cc15e3a934085c24e83bc2bd11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7654efeb428cf98ef64a6d04a92a4c88 |
publicationDate |
2000-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0015839-A1 |
titleOfInvention |
Method for determining susceptibility to bone damage by screening polymorphisms in the vitamin d receptor gene |
abstract |
The present invention relates to a prognostic method and means for determining susceptibility to bone damage in a subject, by screening for polymorphisms in the Vitamin D receptor or collagen Iα1 genes. In particular, the method for determining susceptibility to bone damage comprises analysing the genetic material of a subject to determine which of the B/b, A/a or T/t alleles of the restriction enzyme sites BsmI, ApaI and TaqI respectively are present. The method may further comprise determining which allele is present at the Sp1 restriction site of the collagen Iα1 gene. Specific combinations of the above alleles represent a haplotype which is associated with susceptibility to bone damage. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004065931-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7803538-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02059358-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-02059358-A3 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004065931-A2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004055212-A1 |
priorityDate |
1998-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |