abstract |
The invention relates to a composition comprising at least one thrombocytic growth factor, fibrin and/or one precursor thereof, preferably fibrinogen, and at least one additional polymer and/or one precursor thereof. In a preferred embodiment, the thrombocytic growth factor is reversibly bound to fibrin and/or fibrinogen and to the additional polymer and/or the precursor thereof. The invention also relates to the composition in which the fibrin and/or fibrinogen and the polymer and/or the precursor thereof construct a matrix. In addition, the invention relates to the use of the composition for treating damages in tissues which are characterized by having a low blood flow and/or a diminished ability to regenerate, as well as for treating damages in skin and/or soft tissues. Elastic or hyaline fibrous cartilage and fascial tissue belong, in particular, to these tissues. |