http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0012482-A3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a57bed316ef70b581f2beabe292ffaf8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44bcbbc3c5a767bc337db529d8a82d69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6f17c4e4a702bcae6df3f13f493a74f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_767176a92e07c96a8bb917f6892d23d0 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-56 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-56 |
| filingDate | 1999-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9282e0445a61de71cb84f570e9755673 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_295101d8d70f8183dde97fdfba92f432 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3f69673207daa91b73653b6dfddcaf7 |
| publicationDate | 2000-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | WO-0012482-A3 |
| titleOfInvention | Indazole derivatives with 5-ht2 receptor activity |
| abstract | For use in therapy, a chemical compound of formula (I) wherein R1 and R2 are independently selected from hydrogen and alkyl; R3 is alkyl; R4 to R7 are independently selected from hydrogen, halogen, hydroxy, alkyl, aryl, amino, monoalkylamino, dialkylamino, alkoxy, aryloxy, alkylthio, arylthio, arylsulfoxyl, arylsulfonyl, alkylsulfoxyl, alkylsulfonyl, nitro, cyano, carboxaldehyde, alkylcarbonyl, arylcarbonyl, aminocarbonyl, monoalkylaminocarbonyl, dialkylaminocarbonyl, alkoxycarbonylamino, aminocarbonyloxy, monoalkylaminocarbonyloxy, dialkylaminocarbonyloxy, monoalkylaminocarbonylamino and dialkylaminocarbonylamino, wherein at least one of R4 to R7 is a substituent group other than hydrogen; and R8 is selected from hydrogen and alkyl, and pharmaceutically acceptable salts and prodrugs thereof, other than compounds in which R1 is hydrogen and R2 is -CH2CH(OH)-Ar and other than compounds in which R2 is H and R1 is -CH2CH(OH)-Ar wherein Ar is 3-halophenyl or 3-trifluoromethylphenyl, and the use thereof in therapy, particularly for the treatment of disorders of the central nervous system; damage to the central nervous system; cardiovascular disorders; gastrointestinal disorders; diabetes insipidus, and sleep apnea, and particularly for the treatment of obesity; novel chemical compounds of formula (I). |
| priorityDate | 1998-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.