| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_997afbb06475937aa040a7102b4ff7a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf4ece578a9b5d5d17798deb8d90825f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bcff13f8573db698307f919e6385d5c4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y114-99003
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-44 |
| filingDate |
1999-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfbad73c0d83ed8f83fb8b594994f433
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9633390616c85c64e386a7322d439b16 |
| publicationDate |
2000-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0010613-A2 |
| titleOfInvention |
Inhibition of smooth muscle cell migration by heme oxygenase 1 |
| abstract |
The present method provides a method for inhibiting restenosis associated with mechanical injury of a blood vessel. Human heme oxygenase (I) (HO1) is directly administered at the site of injury. The present inventors have discovered that carbon monoxide generated by HO1 is involved in the molecular pathogenesis of vascular proliferative disorders. By using adenoviral-mediated expression of inducible heme oxygenase 1 in primary vascular smooth muscle cells (vsmc) in vivo, the present inventors demonstrate that in vivo expression of HO1 can be used to treat restenosis. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8187321-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9254202-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8623068-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8206435-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8197881-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8361537-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8052734-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8052735-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7819912-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7850727-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7850728-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8439968-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7896912-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9062089-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007059959-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8449901-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8349390-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9611286-B2 |
| priorityDate |
1998-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |