Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9ed26a2c594d3557755cc9eb40548355 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c7fd38ff393036b78f4fa402ddeeae2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87bfac822c8ffa49f98626d21a8f4e54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a55a82c2516a39faf3bb08c4fcff227e |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-196 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-341 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-341 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-196 |
filingDate |
1999-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c193d39ea929946854bd54e19e856429 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_846a6ea007c36bc56667d1a38cc9d96e |
publicationDate |
2000-03-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0010574-A1 |
titleOfInvention |
The use of loop diuretics for hiv infection |
abstract |
The present invention discloses the efficacy of loop diuretics, such as Furosemide on inhibition of the growth of HIV virus and augmentation of cell growth of ex vivo peripheral blood mononuclear cells (PBMC) isolated from AIDS patients. The infected cells of the patients were compared with healthy donor's PBMC response to Furosemide. PBMC isolated from HIV infected sero-positive patients were cultured ex vivo in the presence of Furosemide. PBMC that were cultured with Furosemide showed similar or greater cell divisions as cells cultured without the drug. PBMC from healthy donors showed an inverse cell growth response, with a significant inhibition of cell growth in the presence of Furosemide. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2367242-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/GB-2367242-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6894030-B2 |
priorityDate |
1998-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |