| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_67e7e5aafd606523adb11541c37e4363
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0917a1008036ff648d40f417099c62fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4cffced8bf73594b036ae50051929895
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ffca183fb6fefcdfbb634d32e0880a53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7641467e74b2b5e8fb2f4c28507f235 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6424 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-64 |
| filingDate |
1999-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf92e51b6de9fc896d105eb43b7546c7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8e649620acfea87116440994a77e44a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_29e19af39cf3fff3d2b9a45e1ff176ec
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72dd460ad8551edc47ba029362dc1136 |
| publicationDate |
2000-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0008134-A2 |
| titleOfInvention |
HUMAN HtrA SERINE PROTEASE |
| abstract |
The subject invention concerns novel materials and methods for the detection of human osteoarthritis and cancer. Specifically, a human HtrA gene and gene product are disclosed which are differentially expressed when comparing osteoarthritic tissue to non-osteoarthritic tissue. A further aspect of the invention concerns compounds which antagonize the biological activity of HtrA protein and methods for identifying these compounds. Another aspect of the present invention concerns pharmaceutical compositions comprising such compounds. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9738727-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10421821-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10421822-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11512143-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2851432-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11377439-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11267803-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2018220034-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10519450-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008067040-A3 |
| priorityDate |
1998-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |