Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c09bed4f78cdcb998ded38dc8023e5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ba8bdab7ff67ed3f60e2933e9c4be6f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d2d15289f7c825c28b1dac1d671c1c71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3ec3b4e7dd4ed9ac1300bc622012823 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4289a396c910b8d5e3224d77e9ebe404 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4716 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4707 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate |
1999-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a99102e384a11e1fc4f39b2489dedd9b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fb01effd8f667d0bba81f5f53cf3341f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b27752487014c7f0f5cf1e4393997093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfc2e3ded3ee7acf8aa7128de91b5fb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1520ea7e2d044c4dcb666d6848fbe0ab |
publicationDate |
2000-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
WO-0004145-A2 |
titleOfInvention |
Myotilin, an actin-organizing protein |
abstract |
The present invention concerns a novel cytoskeletal protein, myotilin, which contains Ig-like domains homologous to a giant sarcomeric structural protein titin. Myotilin is expressed in skeletal and cardiac muscles, it colocalizes with α-actinin in the sarcomeric I-bands and directly interacts with α-actinin. Expression of myotilin in mammalian non-muscle cells and in yeast causes reorganization of actin into thick F-actin bundles and inhibits growth of yeast cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0172320-A1 |
priorityDate |
1998-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |