| abstract |
The present invention provides novel, isolated potassium channel subunits and polynucleotides which identify and encode such subunits. The invention also provides expression vectors and host cells comprising nucleic acid sequences encoding such potassium channels. The invention also provides antibodies directed to the potassium channels and methods of diagnosing and treating diseases associated with activity of such potassium channels. In addition, the invention provides screening assays employing the polypeptide, nucleotide, and antibody compositions, and agonist and antagonist compounds selected by such screening assays. |