| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14c9ad767fb6d5e9dabfb770d4e82252 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6874
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00641
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00637
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00626
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00612
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-0061
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00605
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00722
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00497
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00454
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6872 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6874
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N27-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6872
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 |
| filingDate |
1999-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8bf1f32235b9deaa7af12e189bb9bddc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_46459635b1b269b2f6f3e03bae959dc7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f8ffc73fdf43378ad1f5a1e44ee0b3d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3127663f6faba0910fd56f58e46eca1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_20f3dc9f5a56a6bae54b5fbca1b9fb01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b3896b4eb18c5fc324b0c29f4dbf038b |
| publicationDate |
2000-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0003038-A2 |
| titleOfInvention |
Method and reagents for analyzing the nucleotide sequence of nucleic acids |
| abstract |
Methods and reagents are disclosed which satisfy the need for more sensitive, more accurate and higher through-put analyses of target nucleic acid sequences. The methods and reagents may be generically applied to generally any target nucleic acid sequence and do not require a priori information about the presence, location or identity of mutations in the target nucleic acid sequence. The reagents of the invention are mixtures of natural and mass-modified oligonucleotide precursors having a high level of coverage and mass number complexity. A method is also disclosed for analyzing a target nucleic acid sequence employing the mixtures of natural and mass-modified oligonucleotide precursors and chemical or enzymatic assays to alter the mass of the oligonucleotide precursors prior to mass spectral analysis, generally via MALDI-TOF. The enzymatic assay may be a polymerase extension assay or a ligase assay. The kits for carrying out the methods of the invention are also disclosed. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7138506-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/DE-10015797-B4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7399844-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1251136-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1251136-A2 |
| priorityDate |
1998-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |