| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44858c46e9fc28a6d4532e8cbdf3cd9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_76ba102ea9c02b6633d64bf09c5b89a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9bb03f7a034008928a1e265c6bd3c93 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2770-24222 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-506 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-50 |
| filingDate |
1999-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_565c37499c537cf522b6df082dac245a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89cd90db34b704e13710bf13dd7f9ba0 |
| publicationDate |
2000-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
WO-0001718-A2 |
| titleOfInvention |
Ns4a-ns3 catalytic domain of hepatitis c |
| abstract |
The subject invention concerns modified domains of the polyprotein of the hepatitis C virus. The polypeptides of the invention are directed to modified forms of the NS3 and NS4A domains of the polyprotein. In one embodiment, the NS4A fragment is covalently attached to the NS3 catalytic domain. The NS4A fragment is attached to the N-terminal end of NS3. The subject invention also concerns polynucleotides that encode the NS3/NS4A polypeptides. The invention also pertains to methods of preparing the subject polypeptides and methods for screening for compounds that inhibit the serine protease activity of the NS3 protein. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7491808-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2392589-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8501450-B2 |
| priorityDate |
1998-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |