| abstract |
N-Phenyl-N'-phenylpropylpiperazine derivatives represented by general formula (1) (wherein R1 is lower alkyl; R2 is lower alkoxy; and R3 is cyano, carboxyl or indolecarbonyl); drugs containing the same; and a process for the preparation thereof. The compounds exhibit potent α¿1?-adrenergic receptor blocking activity and are useful in the prevention and treatment of hypertension, congestive heart failure, myocardial ischemia, arrhythmia, angina pectoris, urinary disturbance and frequent urination due to prostatic hypertrophy, and so on. |