| abstract |
The present invention relates to compounds of the Formula (I) or salts thereof pharmaceutically acceptable, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6 , R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24 and m are as defined herein.The novel purine derivatives They are useful for treating abnormal cell growth, such as cancer, in mammals. Other embodiments relate to pharmaceutical compositions containing the compounds and to methods for using the compounds and compositions in the treatment of abnormal cell growth in mammals. |