abstract |
The invention provides modulators for the orphan nuclear ROR receptor and methods for treating ROR-mediated diseases by administering these new ROR modulators to a human or mammal in need thereof. Specifically, the present invention provides cyclic compounds containing carboxamide of Formula (1) to Formula (5) and enantiomers, diastereomers, tautomers, N-oxides, solvates and pharmaceutically acceptable salts thereof. |