abstract |
3-Heteroaroylamino-propionic acid derivatives substituted with oxygen and their use as pharmaceuticals. The present invention relates to compounds of formula I, wherein A, D, E, G, R10, R30, R40, R50 and R60 have the meanings indicated in the claims, which are valuable active pharmaceutical compounds. They are cathepsin A protease inhibitors, and are useful, for example, for the treatment of diseases such as atherosclerosis, heart failure, kidney diseases, liver diseases or inflammatory diseases. The invention further relates to processes for preparing the compounds of formula I, their use and pharmaceutical compositions comprising them. |