| abstract |
The present invention relates to salts of 3- (3-amino-2- (R) -hydroxy-propyl) -1- (4-fluoro-phenyl) -8- (8-methyl-naphthalen-1-ylmethyl) - 1,3,8-triaza-spiro [4.5] decan-4-one, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by NOP, for example depression, anxiety, alcohol abuse, etc. The present invention further relates to process (s) for the preparation of 3- (3-amino-2- (R) -hydroxy-propyl) -1- (4-fluoro-phenyl) -8- (8-methyl- naphthalen-1-ylmethyl) -1,3,8-triaza-spiro [4.5] decan-4-one and its corresponding salts. |