abstract |
The invention relates to a compound of Formula I wherein m is 1-2 and each R1 is a group such as cyano, halogen, trifluoromethyl, heterocyclic and hererocyclyloxy; R2 is trifluoromethyl or (C1-6) alkyl, R3 is hydrogen or halogen; and R4 is isoxazolyl; or a pharmaceutically acceptable salt thereof; procedures for its preparation, pharmaceutical compositions containing them and their use in the treatment of diseases or conditions mediated by cytokines. |