| abstract |
The present invention relates to a compound of formula (1) wherein R1, R2, R3, R4, R5, and n are as defined in the description and claims to the pharmaceutically acceptable salts and / or esters thereof. The compounds are useful for the treatment of diseases that are associated with cysteine portazas such as osteoporosis, osteoarthritis, rheumatoid arthritis, tumor metastasis, glomerulonephritis, atherosclerosis, myocardial infarction, angina pectoris, unstable angina pectoris, plaque rupture heart attack atherosclerotic, transient ischemic attacks, amaurosis fugax, peripheral arterial occlusive disease, restenosis after angioplasty and deposition, formation of abdominal aortic aneurysm, inflammation, autoimmune diseases of the eye, fundus tissue and respiratory diseases |