abstract |
The present invention relates to certain benzamido-piperidine-containing compounds and related compounds exhibiting activity as NK-1 receptor antagonists, (eg, substance P receptor antagonists), to pharmaceutical compositions containing them, and to their use in the treatment and prevention of disorders of the central nervous system, inflammatory disorders, cardiovascular disorders, ophthalmic disorders, gastrointestinal disorders, disorders caused by helicobacter pylori, disorders of the immune system, urinary incontinence, pain, migraine, emesis, angiogenesis and other disorders . |