| abstract |
Indazole compounds that modulate and / or inhibit the activity of certain protein kinases were described. These compounds and pharmaceutical compositions containing them are capable of mediating the signaling transduction of tyrosine kinase and thus modulate and / or inhibit the proliferation of superfluous cells. The invention is also directed to the therapeutic and drug use of pharmaceutical compositions containing such compounds, and to methods of treating cancer and other diseases associated with superfluous angiogenesis and / or cell proliferation, such as diabetic retinopathy, neovascular glaucoma, arthritis rheumatoid, and psoriasis, for administering effective amounts of such compounds. |