Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_953230235e857bef7e05e30b9068d499 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-12 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-473 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-40 |
filingDate |
1999-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cef1c11d301bc77460182cea8aa4f0c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17103928d668c31aa761240ae4eddac2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2280c8f32482ce390d37c95edf4240a |
publicationDate |
1999-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
UY-25374-A1 |
titleOfInvention |
APOMORPHINE COMPOSITIONS USEFUL IN THE TREATMENT OF FEMALE SEXUAL DYSFUNCTION |
abstract |
Sublingual dosage form for the amelioration of female sexual dysfunction, comprising apomorphine or a pharmaceutically acceptable acid addition salt thereof, contained in an amount of 2 milligrams to 12 milligrams of ampomorphine, so that the useful amount is sufficient to increase intraclitorial blood flow and vaginal wall blood flow produced by stimulation of said woman, but less than the amount that causes nausea; the dose may also comprise a beta-cyclodextrin (more particularly hydroxypropyl-beta-cyclodextrin). The dosage form can also include mannitol and ascorbic acid. Especially included is a dosage comprising ampomorphine or addition salt thereof in an amount sufficient to maintain the plasma concentration between 1 to 2 nanograms per millimeter of plasma during sexual activity. |
priorityDate |
1998-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |