abstract |
Procedure for preparing derivatives of 1,3 thiazoles or 1,3 oxazoles comprising reducing a precursor thereof with complex hydride. The invention relates to an intermediate compound of formula (III) or one of its tautomeric forms, or of its salts, or of its solvates, where J is O or S; T represents a substituted or unsubstituted aryl group, for the preparation of a compound of formula (I) or a pharmaceutically acceptable salt thereof, where J is O or S; T is substituted aryl and T1 is O or S. Example: 5- (4- (2- (N-methyl-N- (2-pyridyl) amino) ethoxy) benzyl) -2,4-thiazolidinedione (IA) by reduction 5- (4- (2- (N-methyl-N- (2-pyridyl) amino) ethoxy) benzylidine) 2,4-thiazolidinedione (IIB) |