| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-546
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-545
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-00 |
| filingDate |
1993-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_880edd7fff84eefdb7811ef6187e0655
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36f25d3328795f599a813fb5289c768b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41fa963d641b7ef390a7f62c8e4106f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72cb4cbfff778187f0daed83e161bcd8 |
| publicationDate |
1994-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
UY-23672-A1 |
| titleOfInvention |
PROCEDURE FOR THE PREPARATION OF CEPHALOSPORIN DERIVATIVES |
| abstract |
Process for the preparation of cephalosporin derivatives of general formula (I) (figure 1), and corresponding easily hydrolyzable and pharmaceutically acceptable esters as well as salts and hydrates of these compounds, where R represents one of the groups represented in figure 2; the process comprises: a- acylating a compound of general formula (II) (figure 3), where R 'is a group corresponding to R that contains an unsubstituted amino group in position 7 of the cephalosporin nucleus, or a respective acid addition salt ; b- or converting a compound of formula (I) into a salt or hydrate or hydrate of said pharmaceutically acceptable salt. Non-limiting example: (6R-trans) -3-hydroxymethyl-7 - [[(1,1-dimethyl-ethoxy-carbonyl] amino] -8-oxo-5-thia-1-azabicyclo [4.2.0] oct -2-en-2-carboxylic The final products according to the process are useful in the preparation of a medicament for the treatment and prophylaxis of infectious diseases. |
| priorityDate |
1992-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |