http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-RE39383-E
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_84d9adaa7e7ce01ce8020f5c721aba10 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate | 2004-03-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2006-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d5e5f6d96608f111958c7e6986694a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62670b10289b74e4c51aefaea5fa325d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ffe656660b2a4f854724da494b04a19f |
| publicationDate | 2006-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-RE39383-E |
| titleOfInvention | Process for 6-O-alkylation of erythromycin derivatives |
| abstract | A procedure for preparing 6-O-alkyl erythromycin compounds having the formula: n n nwherein R 1 is a loweralkyl group, R 2 and R 3 an independently hydrogen or a hydroxy-protecting group, except that R 2 and R 3 may not both be hydrogen simultaneously; Y is oxygen or a specifically substituted oxime; and Z is hydrogen, hydroxy or protected-hydroxy; by reaction of the compound wherein R 1 is hydrogen with an alkylating reagent, is the presence of a strong alkali metal base and also in the presence of a weak organic amino base, in a suitable stirred or agitated polar aprotic solvent, or a mixture of such polar aprotic solvents maintained at a reaction temperature and for a period of time sufficient to effect alkyation. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009054634-A1 |
| priorityDate | 1995-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 139.