| abstract |
PCT No. PCT/JP94/01049 Sec. 371 Date Jun. 21, 1995 Sec. 102(e) Date Jun. 21, 1995 PCT Filed Jun. 29, 1994 PCT Pub. No. WO95/01323 PCT Pub. Date Jan. 12, 1995An object of the present invention is to provide a safe method of commercially producing optically active aminoalcohol derivatives, which serve as intermediates for the synthesis of medicinal chemicals such as the immunopotentiating anticancer agent bestatin, in a simple and easy manner in high yields and with high levels of selectivity. The present invention consists in a method of producing 3-amino-1-nitro-4-phenyl-2-butanol derivatives of the general formula (1) wherein R1 and R2 each independently represents a hydrogen atom or an amino group protecting group, and a method of producing 3-amino-2-hydroxy-4-phenylbutyric acid derivatives derivable therefrom. |